Andrographis paniculata [Pinyin name] ChuÄn XÄ«n Lián [English name] HERBA ANDROGRAPHIS [Alias] Helianthus annuus, first sight hi, tongue-cut sword, bitter grass, bitter gall grass, quartet grass [Source] This product is the Andrographis paniculata Mustard herb) Andrographis paniculata (Burm. F.) Dry above-ground part of Nees. The stems and leaves are harvested and dried in the early autumn and dried. ã€Properties】 The stem of this product is square columnar, multi-branched, 50-70 cm long, with slightly enlarged nodes; brittle and easy to break. Single leaf opposite, petiole short or nearly sessile; leaf blade shrunken and fragile, intact lanceolate or oval lanceolate when unfolded, length 3-12 cm, width 2-5 cm, apex tapering, base wedge-shaped Downward, whole or wavy; green on top, grayish green on bottom, smooth on both sides. Slight gas, bitter taste. [Identification] (1) The cross-section of the leaves of this product: the upper epidermal cells are square or rectangular, the lower epidermal cells are smaller, and the upper and lower epidermis have crystal cells containing round, oblong or rod-shaped stalactite; and there are Glandular scales, sometimes with non-glandular hairs. The palisade tissue is 1 to 2 rows of cells, which penetrates above the main vein; the sponge tissue is loosely arranged. The main veins are vascular bundles of external toughness, which are groove-shaped, and there are crystal cells above the xylem. Leaf surface preparation: both upper and lower epidermis have enlarged crystal cells, containing large snail-shaped stalactites, about 36μm in diameter, about 180μm in length, with umbilical-like spots on the larger end, lamellar, stomata Densely distributed, straight shaft type, the size of the secondary guard cells is very different, and there are also infinitives. The glandular squamous head is spheroid, with 4, 6 (8) cells, and the diameter is up to 40 μm; the stem is extremely short. The non-glandular hairs 1 to 4 cells are about 160 μm long, the base diameter is about 40 μm, and the surface has keratinous texture. (2) Take the test solution under [Content Determination] as the test solution. Another 0.5 g of Andrographis paniculata control medicinal material was added, 30 ml of ethanol was added, ultrasonic treatment was performed for 30 minutes, filtered, and the filtrate was concentrated to about 50 ml as a control medicinal solution. Then take dehydrated andrographolide and andrographolide reference substance, add absolute ethanol to make a mixed solution containing 1mg per 1ml, as a reference solution. According to the thin layer chromatography (Appendix â…¥ B) test, draw 6μl of the test solution and the reference medicinal solution and 4μl of the reference solution, respectively, and spot them on the same silica gel GF254 thin layer board with sodium carboxymethyl cellulose as the binder , Using chloroform-ethyl acetate-methanol (4: 3: 0.4) as the developing agent, unfold, remove, dry, and inspect under ultraviolet light (254nm). In the chromatogram of the test product, spots of the same color were displayed on the corresponding positions of the chromatogram of the reference medicinal material and the chromatogram of the reference substance; sprayed with 2% 3,5-dinitrobenzoic acid ethanol solution and 2mol / L potassium hydroxide solution The same amount of mixed solution (prepared before use), immediately observed in the sun, for the test product chromatography, in the corresponding position of the control drug chromatography and the control substance chromatography, respectively show the same color spots. ã€Processing】 Remove impurities, wash, cut into sections, and dry. ã€Sexual taste】 Bitter, cold. ã€Missing】 Meridian, lung, large intestine and bladder meridian. ã€Functions】 Clear heat and detoxify, cool blood and reduce swelling. For colds and fever, sore throat, sore tongue, sore cough and labor, diarrhea and dysentery, hot astringent pain, carbuncle swollen sores, poisonous snake bites. ã€Usage and dosage】 6 ～ 9g; appropriate amount for external use. [Storage] Store in a dry place. [Remarks] (1) Oral andrographis paniculata 0.5 to 1 to 2 hours may cause side effects such as nausea and loss of appetite; patients with stomach and duodenal ulcer disease should not take it.
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