1. Microbiological examination including the isolation and virulence identification of pathogenic bacteria. Specimens were collected from the pharynx and stained with Gram, methylene blue, or Neisseria for microscopic examination, and simultaneously inoculated into the Lu's serum bevel and potassium tellurite differential culture medium. Black colonies can be observed. After the bacteria are isolated, virulence identification is carried out to distinguish between toxigenic strains and non-toxigenic strains.
2. Prevention principles
(1) Active immunization prevention: The application of diphtheria toxoid or DPT vaccine in accordance with the procedures for active immunization prevention has achieved good results. China has included diphtheria as a planned immunization prevention disease.
(2) Passive immune prevention: Intramuscular injection of diphtheria antitoxin is used for passive immune prevention for close contacts. Large doses of diphtheria antitoxin can also be used for early treatment of diphtheria patients.
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